The Manor team has been rocked by the shock resignation of its founders and bosses John Booth and Graeme Lowdon.
Motorsport.com understands that despite the hard work both men have done to keep the team alive and push it forward with Mercedes for 2016, they have grown frustrated with the direction new owner Stephen Fitzpatrick wants to take the outfit.
Energy firm boss Fitzpatrick helped form a key part of the rescue package that was put together by Lowdon and Booth last winter, which ensured the team's return to the grid this season.
But despite the recovery from administration, and the efforts made to sort out its engine deals and high-profile staffing recruitment, Lowdon and Booth are understood to be unhappy that interest from investors to buy in to the team has not been actioned upon.
It is believed the pair reckon that a big cash injection like this would be perfect for helping the team move forward to become a solid midfield contender.
Motorsport.com revealed earlier this year that race promoter Tavo Hellmund and financier James Carney were heading a group of United States investors that wanted to buy into the team.
However, despite a solid financial package, their offer was not accepted – despite the huge financial boost it would have given the team.
It is understood another separate offer has also been rebuffed.
Lowdon and Booth declined to comment on the speculation about their future in Mexico, but both are continuing to work with the outfit for now.